Dr. Pathakota Gireesh Babu
Scientist Fish Genetics and Biotechnology
M.F.Sc (Fish Genetics and biotechnology);
Ph. D. (Fish Biotechnology)

+91 2636-1447 Extn: 490(O)

girishbabu@cife.edu.in

Research Interests

  • Bio-prospecting of genes and promoters
  • Omics approaches for understanding the biological impact of microplastic pollutants
  • RNA interference and CRISPR tools for various applications including vaccines/ reproductive maturation / gene editing etc

Research Papers

  • Hoque F., Pawar N., Pitale P., Dutta R., Sawant B., Gireesh-Babu P., Chaudhari A., Sundaray J.K., 2020. Pathogenesis and expression profile of selected immune genes to experimental Edwardsiella tarda infection in iridescent shark Pangasianodon hypophthalmus. Aquaculture Reports 17: 100371.
  • Meena L.L., Goswami M., Chaudhari A., Nagpure N.S. Gireesh-Babu P. Dubey A., Das D.K., 2020. Development and characterization of a new DRCF cell line from Indian wild strain zebrafish Danio rerio (Hamilton 1822). Fish Physiol Biochem., https://doi.org/10.1007/s10695-020-00792-x
  • Ram, R., Pavan-Kumar, A., Jaiswar, A.K., Gireesh-Babu, P., Krishna, G., Chaudhari, A., 2020. Identification of fish and shellfish larvae from mangroves using DNA barcodes. Journal of Coastal Research, 00(0), 000–000. Coconut Creek (Florida), ISSN 0749-0208.
  • Wisdom, K.S., Bhat, I.A., Chanu, T.I., Kumar P., Gireesh-Babu P., Nayak S.K., Walke P., Sharma R., 2020. Chitosan grafting onto single-walled carbon nanotubes increased their stability and reduced the toxicity in vivo (catfish) model. International Journal of Biological Macromolecules, 155: 697-707.
  • Jafer Y. D., Purushothaman C.S., Kumar, S.H., Irfan A. B., Gireesh Babu P., Ganie P. A., Bhat R. A. H., Vennila A., 2019. A combined approach of 16S rRNA and a functional marker gene, soxB to reveal the diversity of sulphur oxidising bacteria in thermal springs. Archives of Microbiology, 201(7):951-967.
  • Saravanan, K., Rajendran, K. V., Gireesh-Babu, P., Purushothaman, C. S., Makesh, M., 2019. Molecular characterization and expression analysis of secretory immunoglobulin M (IgM) heavy chain gene in rohu, Labeo rohita. Animal Biotechnology, DOI:10.1080/10495398. 2019.1612411.
  • Rao B.M., Kole S., Gireesh-Babu P., Sharma R., Tripathia G., Bedekar, M.K., 2019. Evaluation of persistence, bio-distribution and environmental transmission of chitosan/PLGA/pDNA vaccine complex against Edwardsiella tarda in Labeo rohita. Aquaculture 500: 385–392.
  • Kumar, P., Wisdom, K.S., Bhat, I.A., Gireesh-Babu P., Nayak, S.K., Reang, D., Nagpure, N.S. and Sharma, R., 2019. Molecular characterization of gonadotropin-inhibitory hormone (GnIH) gene and effect of intramuscular injection of GnIH peptide on the reproductive axis in Catla catla. Animal biotechnology, pp.1-15. doi: 10.1080/10495398.2019.1597730.
  • Haldar, C., Das, S.P., Pillai, B.R., Pavan-Kumar, A., Gireesh-Babu, P., Das, P. and Chaudhari, A., 2019. Single-nucleotide polymorphisms linked to body weight revealed in growth selected Macrobrachium rosenbergii. Aquaculture International, pp.1-12.
  • Acharya, A. P., Pavan-Kumar, A., Gireesh-Babu, P., Joshi, C.G., Chaudhari, A. and Krishna, G., 2019. Population genetics of Indian giant river-catfish, Sperata seenghala (Sykes, 1839) using microsatellite markers. Aquatic Living Resources, 32 (4). https://doi.org/10.1051/alr/2019002
  • Agarwal D., Gireesh-Babu P., Pavan-Kumar A., Koringa P., Joshi C.G., Gora A., Bhat I.A., Chaudhari A., 2018. Molecular characterization and expression profiling of 17-beta-hydroxysteroid dehydrogenase 2 and spermatogenesis associated protein 2 genes in endangered catfish, Clarias magur (Hamilton, 1822). Animal Biotechnology, DOI: 10.1080/10495398.2018.1545663
  • Acharya A.P., Pavan-Kumar A., Joshi C.G., Namrata P., Chaudhari A., Krishna G., 2018. Development and characterization of 15 novel polymorphic microsatellites for Giant river-catfish Sperata seenghala (Sykes, 1839) using next-generation sequencing approach. J Appl Ichthyol., 00: 1–3.
  • Bhat I.A., Rather M.A., Nazir M.I., Gireesh-Babu P., Goswami M., Sundaray J.K., Sharma R., 2018. Cloning, characterisation, docking and expression analysis of 3-betahydroxysteroid dehydrogenase during ontogenetic development and annual reproductive cycles in catfish, Clarias batrachus. Theriogenology 105, 34-44.
  • Mir I.N., Srivastava P.P., Bhat I.A., Muralidhar A.P., Varghese T., Gireesh-Babu P., Jain K.K., 2018. Expression and activity of trypsin and pepsin during larval development of Indian walking catfish (Clarias magur). Aquaculture 491, 266–272.
  • Priyadarshi, H., Das, R., Pavan-Kumar, A., Gireesh-Babu, P., Javed, H., Kumar, S., Marappan, M., Somdutt., Krishna G. and Chaudhari, A., 2017. Silencing and augmentation of IAG hormone transcripts in adult Macrobrachium rosenbergii males affects morphotype transformation. Journal of Experimental Biology, 15, 4101-4108.
  • Kumari K., Gireesh-Babu P., Kumar S., Krishna G., 2017. Gene structure and comparative and phylogenetic analyses of Catla catla CYP1A full-length cDNA and its responsiveness to benzo(a)pyrene and copper sulphate at early developmental stages. Fish Physiol Biochem, DOI 10.1007/s10695-017-0416-6.
  • Rather M.A., Bhat I.A., Gireesh Babu P., Chaudhari A., Sundaray J.K., Sharma R., 2016. Molecular characterization of kisspeptin gene and effect of nano-encapsulted kisspeptin-10 on reproductive maturation in Catla catla. Domestic Animal Endocrinology, In Press.
  • Rasal A., Suvra Roy, R.S. Rana, S. Murali, Gopal Krishna, Subodh Gupta, Gireesh-Babu P., 2016. Molecular cloning and nutritional regulation of putative Δ6 desaturase mRNA from striped catfish (Pangasianodon hypophthalmus). Aquaculture 451: 413–420.
  • Rekha Das, Gopal Krishna, Himanshu Priyadarshi, P Gireesh-Babu, A Pavan-Kumar, K V Rajendran, A K Reddy, M Makesh, Aparna Chaudhari (2015). Captive maturation studies in Penaeus monodon by GIH silencing using constitutively expressed long hairpin RNA. Aquaculture 448(448):512-520.
  • Sudhanshu Raman, A. Pavan-Kumar, Prakash G. Koringa, Namrata Patel, Tejas Shah, Rajeev K. Singh, Gopal Krishna, C. G. Joshi, P. Gireesh-Babu, Aparna Chaudhari, W. S. Lakra (2015). Ion torrent next-generation sequencing reveals the complete mitochondrial genome of endangered mahseer Tor khudree (Sykes, 1839). Mitochondrial DNA DOI:10.3109/19401736.2015.1060455

Other Publications

Popular articles
  • Chaudhari A. and Gireesh-Babu P., 2012. Long-hairpin RNA expressing plasmid vaccine to control White spot syndrome virus in tiger shrimp. Virus Research News, Indian Virological Society, Vol. 1: 3-4.
  • Chaudhari A. and Gireesh-Babu P. and Krishnan P., 2013. Long hairpin RNA expressing plasmid vaccine to control WSSV in P. monodon. CIFE Technologies and Innovative Products for Fish Farmers and Entrepreneurs. CIFE. Abstract 15, p28.
Book Chapters
  • Chaudhari A., Gireesh-Babu P., Pavan-Kumar A., 2015. Design and Construction of Shrimp Antiviral DNA Vaccines Expressing Long and Short Hairpins for Protection by RNA Interference In Vaccine Design: Methods and Protocols. Ed. Sunil Thomas.
  • Pavan-Kumar, A., Gireesh-Babu, P., Jaiswar, A. K., Chaudhari, A., Krishna, G. and Lakra, W.S. 2016. DNA Barcoding of Marine Fishes: Prospects and Challenges. In: DNA Barcoding in Marine Perspectives: Assessment and conservation of Biodiversity, Springer, Switzerland, pp.285-299. DOI : 10.1007/978-3-319-41840-7_17
  • Chaudhari A., Gireesh-Babu P., Pavan-Kumar A., 2019. Application of RNA interference vaccines in aquaculture In Advances in Fish Research, Ed. B.P. Mohanty, Vol. VII. Pages 317–333; Narendra Publishing House, Delhi, India.
Sr. No. Title of the Project Capacity Status
Institutional
1. Identification and validation of tri and tetra-nucleotide microsatellite loci in Clarias batrachus PI Ongoing
2. DNA Barcoding of Selected Fishes from Indian Coast Co-PI Ongoing
3. SNP mining within reported coding sequences of freshwater prawn Macrobrachium rosenbergii using next generation sequencing Co-PI Ongoing
4. Genetic Evaluation and Genetic characterization of two new candidate species for aquaculture Macrobrachium villosimanus & Osteobrama belangeri (Pengba) Co-PI Completed
5. Performance Evaluation and Mass selection for Important Economic traits in Penaeus Species Co-PI Completed
Externally Funded
6. Development of nanodelivery system of DNA-based RNAi vaccine against WSSV in tiger shrimp Penaeus monodon Co-PI (DBT) Ongoing
7. Development of optical fibre based bacterial biosensors for heavy metal pollution Co-PI (DBT) Ongoing
8. Functional validation of 4 novel proteins associated with salt homeostasis in P. monodon Co-PI (NAIP) Completed
9. Development and use of fluorescent transgenic zebrafish biosensors for monitoring genotoxic pollutants Co-PI (NAIP) Completed

Others