Research Papers

• Leya, T., Ahmad, I., Sharma, R., Tripathi, G., Kurcheti, P.P., Rajendran, K.V. and Bedekar, M.K., 2020. Bicistronic DNA vaccine macromolecule complexed with poly lactic-co-glycolic acid-chitosan nanoparticles enhanced the mucosal immunity of Labeo rohita against Edwardsiella tarda infection. International Journal of Biological Macromolecules.
• Kumari, R., Kole, S., Soman, P., Rathore, G., Tripathi, G., Makesh, M., Rajendran, K.V. and Bedekar, M.K., 2018. Bicistronic DNA vaccine against Edwardsiella tarda infection in Labeo rohita: construction and comparative evaluation of its protective efficacy against monocistronic DNA vaccine. Aquaculture, 485, pp.201-209.
• Kole, S., Anand, D., Sharma, R., Tripathi, G., Makesh, M., Rajendran, K.V. and Bedekar, M.K., 2017. Tissue specific expression profile of some immune related genes in Labeo rohita to Edwardsiella tarda infection. Fish & shellfish immunology, 66, pp.575-582.
• Yadav, S., Tantwai, K., Rajput, L.S., Bedekar, M.K., Kumar, S., Gontia, I. and Tiwari, S., 2011. Molecular cloning of phytase gene from Bacillus subtilis NCIM-2712. Journal of Phytology.
• Kole, S., Kumari, R., Anand, D., Kumar, S., Sharma, R., Tripathi, G., Makesh, M., Rajendran, K.V. and Bedekar, M.K., 2018. Nanoconjugation of bicistronic DNA vaccine against Edwardsiella tarda using chitosan nanoparticles: evaluation of its protective efficacy and immune modulatory effects in Labeo rohita vaccinated by different delivery routes. Vaccine, 36(16), pp.2155-2165.
• Mushtaq, Z., Krishnan, R., Prasad, K.P., Bedekar, M.K. and Kumar, A.P., 2018. Molecular cloning, characterization and expression profiling of galectin-9 gene from Labeo rohita (Hamilton, 1822). Fish & shellfish immunology, 76, pp.287-292.
• Jain, S.K., Jain, H., Kumar, D., Bedekar, M.K., Pandey, A.K. and Sarkhel, B.C., 2015. Quantitative evaluation of myostatin gene in stably transfected caprine fibroblast cells by anti-myostatin shRNA. Applied biochemistry and biotechnology, 177(2), pp.486-497.
• Sahare, A.A., Bedekar, M.K., Jain, S.K., Singh, A., Singh, S. and Sarkhel, B.C., 2015. Inhibition of infectious bursal disease virus by vector delivered SiRNA in cell culture. Animal biotechnology, 26(1), pp.58-64.
• Bedekar, M.K., Soman, P., Kole, S., Anand, D., Tripathi, G., Makesh, M. and Rajendran, K.V., 2018. Evaluation of interferon gamma (IFN-γ) of Labeo rohita as an immunomodulator: in vitro expression model. Aquaculture International, 26(6), pp.1401-1413.
• Rao, B.M., Kole, S., Gireesh-Babu, P., Sharma, R., Tripathi, G. and Bedekar, M.K., 2019. Evaluation of persistence, bio-distribution and environmental transmission of chitosan/PLGA/pDNA vaccine complex against Edwardsiella tarda in Labeo rohita. Aquaculture, 500, pp.385-392.
• Jain, S.K., Jain, H. and Bedekar, M.K., 2016. Phylogenetic analysis of S1 gene of infectious bronchitis virus reveals emergence of new genotype. International Journal of Agriculture, Environment and Biotechnology, 9(5), pp.719-723.
• Syed, Z., Venkatesh, G., Murugkar, H.V., Bedekar, M.K., Nagarajan, S. and Dubey, S.C., 2012. Prokaryotic expression and characterisation of recombinant M1 protein of an Indian H5N1 avian influenza virus. The Indian Journal of Animal Sciences, 82(12).
• Singh, A., Bedekar, M., Sharma, R., Sarkhel, B., Singh, S. and Jain, S., 2012. Detection of very virulent infectious bursal disease virus from a field outbreak in Central India. Acta Veterinaria Hungarica, 60(1), pp.165-174.
• Jain, S.K., Bedekar, M.K., Hemlata, J. and Tripathi, S.M., 2010. Cloning of S1 gene of avian infectious bronchitis virus. Indian Veterinary Journal, 87(8), pp.745-747.
• Kadam, M., Shardul, S., Bhagath, J.L., Tiwari, V., Prasad, N. and Goswami, P.P., 2009. Coexpression of 16.8 kDa antigen of Mycobacterium avium paratuberculosis and murine gamma interferon in a bicistronic vector and studies on its potential as DNA vaccine. Veterinary research communications, 33(7), p.597.
• Jain, S.K., Jain, H., Kumar, D., Bedekar, M.K., Pandey, A.K. and Sarkhel, B.C., 2015. Quantitative evaluation of myostatin gene in stably transfected caprine fibroblast cells by anti-myostatin shRNA. Applied biochemistry and biotechnology, 177(2), pp.486-497.
• Bedekar, M.K., Soman, P.K., Rajendran, K.V., Tripathi, G. and Makesh, M., 2015. Molecular characterization of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) gene of field isolate of Edwardsiella tarda. Advances in Bioscience and Biotechnology, 6(02), p.89.
• Prusty, B.R., Kumar, D., Palai, T.K., Jena, S.C., Bedekar, M.K., Singh, S. and Sarkhel, B.C., 2014. CpG methylation analysis at the putative differential methylated region of the Xist gene in goats (Capra hircus) somatic cells. Veterinarski arhiv, 84(4), pp.365-376.
• Sreedharan, K., Deepika, A., Paria, A., Bedekar, M.K., Makesh, M. and Rajendran, K.V., 2018. Ontogenetic and expression of different genes involved in the Toll pathway of black tiger shrimp (Penaeus monodon) following immersion challenge with Vibrio harveyi and white spot syndrome virus (WSSV). Agri Gene, 8, pp.63-71.
• Banu, H., Anand, D., Bedekar, M.K., Rajendran, K.V. and Makesh, M., 2017. Monoclonal antibodies against recombinant GAPDH of Edwardsiella tarda reveal the conserved nature of the protein. Food and Agricultural Immunology, 28(4), pp.685-698.

Other Publications

• Singh, S. and Bedekar, M.K., 2012. DNA microarray and its applications in disease diagnosis. IJSR, 3, pp.1572-1573.
• Bedekar, M.K. and Makesh, M., Significance of bioinformatics in the detection of microbes. Volume: 49 Research Journal, p.1.
• Kole, S., Kumari, R. and Bedekar, M.K., Advances In Aquatic Animals.
• Bedekar, M.K., Kole, S. and Tripathi, G., 2020. Biotechnological approaches to fish vaccine. In Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries (pp. 407-419). Academic Press.

• Development of dual combination vaccine for protection of Labeo rohita to bacterial pathogens Flavobacterium columnare and Edwardsiella tarda.Funding agency ICAR Consortia platform for vaccine and diagnostics duration 2015-2021
• Characterization of mucosal immunoglobins in Tilapia and development of ELISA for diagnosis of Tilapia lake virus (TiLV) infection (Co-Principal Investigator) funding agency : DBT, GOV, India 2019-22
• Novel Molecular Approaches for Advancing Prediction and Mitigation of Disease Outbreaks in Aquaculture for Small Scale Farmers. Funding agency DBT, Newton fund, 2016-2020
• Understanding molecular basis of host-pathogen environment interaction of Tilapia lake virus disease funding agency National Agricultural Science Fund (NASF), 2019-2021

Others

Significant achievements in research & development

• Development of vaccine for bacterial pathogens of fish.
• Development of diagnostics for fish and poultry pathogens

Honours / Awards

• Best presentation award for research paper “Evaluation of Two DNA Vaccine Constructs in Labeo rohita against Edwardsiella tarda during International conference of Molecular Virology and Microbiology held at Bangkok, Award given by World Academy of Science, engineering and technology: 18-19 December 2017
• Institutional Best Scientist Award at Institute for year 2017-18.