Dr. Arvind A. Sonwane
B.V.Sc. & A.H., M.V.Sc., Ph.D. (Animal Biotechnology)
Principal Scientist
Fish Genetics and Biotechnology Division

Phone (Office): 91 22 26361446/7/8 | Extn: 490

arvind.sonwane@icar.gov.in / arvind@cife.edu.in / arvind2002@gmail.com

Research Interests

  • Genome Engineering

Academics

Courses being taught by you
  • FBT 501 Fundamentals of Molecular Biology 2+1
  • FBT 503 Gene Structure and Regulation of Expression 2+1
  • FBT 506 Bioinformatics Tools in Genetic Engineering 1+1
  • FBT 602 Advances in Cell Biology 2+1
  • FBT 603 Genetic Engineering of Bacteria and Viruses 2+1
Student Guided (Only numbers)
  • 02

Research Papers

  • Gopi B, Vir Singh R, Kumar S, Kumar S, Chauhan A, Sonwane A, Kumar A, Bharati J, Vir Singh S. (2022). Effect of selected single nucleotide polymorphisms in SLC11A1, ANKRA2, IFNG and PGLYRP1 genes on host susceptibility to Mycobacterium avium subspecies paratuberculosis infection in Indian cattle. Vet Res Commun. 2022 Feb;46(1):209-221. doi: 10.1007/s11259-021-09849-5. Epub 2021 Oct 30. PMID: 34718924.
  • Punetha M, Kumar S, Paul A, Jose B, Bharati J, Sonwane A, Green JA, Whitworth K, Sarkar M. (2021). Deciphering the functional role of EGR1 in Prostaglandin F2 alpha induced luteal regression applying CRISPR in corpus luteum of buffalo. Biol Res., 54(1):9. doi: 10.1186/s40659-021-00333-7. PMID: 33712084.
  • Kumar A, Kumar S, Singh RV, Chauhan A, Kumar A, Sonwane A, K I, Singh R. (2021). Investigation of genetic polymorphism at β-casein A1/A2 loci and association analysis with production & reproduction traits in Vrindavani crossbred cows. Anim Biotechnol. 2021 Apr 30:1-9. doi: 10.1080/10495398.2021.1917423. Epub ahead of print. PMID: 33928837.
  • Ahmad SF, Panigrahi M, Chhotaray S, Pal D, Chauhan A, Sonwane A, Parida S, Bhushan B, Gaur GK, Mishra BP, Singh RK. Population structure and admixture analysis in Frieswal crossbred cattle of India - a pilot study. (2020). Anim Biotechnol. 2020 Feb; 31(1):86-92. doi: 10.1080/10495398.2018.1538013. Epub 2018 Nov 16. PMID: 30444183.
  • Kumar S, Punetha M, Jose B, Bharati J, Khanna S, Sonwane A, Green JA, Whitworth K, Sarkar M. (2020). Modulation of granulosa cell function via CRISPR-Cas fuelled editing of BMPR-IB gene in goats (Capra hircus). Sci Rep., 10(1):20446. doi: 10.1038/s41598-020-77596-9. PMID: 33235250
  • Punetha M, Chouhan VS, Sonwane A, Singh G, Bag S, Green JA, Whitworth K, Sarkar M. (2020). Early growth response gene mediates in VEGF and FGF signaling as dissected by CRISPR in corpus luteum of water buffalo. Sci Rep., 10(1):6849. doi: 10.1038/s41598-020-63804-z. PMID: 32321973.
  • Adesh Kumar, Ran Vir Singh, Anuj Chauhan, K Ilayakumar, Sushil Kumar, Amit Kumar, Arvind Sonwane, Subodh Kumar, Manjit Panigrahi & Bharat Bhushan (2020). Genetic association analysis reveals significant effect of β-casein A1/A2 loci on production & reproduction traits in Frieswal crossbred cows, Biological Rhythm Research, 51:8, 1259-1272, DOI: 10.1080/09291016.2019.1571705.
  • Pandey S, Ahmad Bhat I, Kumar Bharti M, Shabir U, Ahmad Peer B, Baiju I, Sonwane A, Chandra V, Sai Kumar G, Taru Sharma G. (2020). Progesterone modulates adhesion molecules in uterine epithelial cells and in vitro embryo production in buffalo. Reprod Domest Anim., 55(7):833-843. doi: 10.1111/rda.13691. Epub 2020 May 18. PMID: 32335951
  • Pandey Y, Pooja AR, Devi HL, Jalmeria NS, Punetha M, Kumar S, Paul A, Kumar K, Sonawane A, Samad HA, Singh G, Bag S, Sarkar M, Chouhan VS. (2020). Expression and functional role of IGFs during early pregnancy in placenta of water buffalo. Theriogenology, 161:313-331. doi: 10.1016/j.theriogenology.2020.12.013. Epub 2020 Dec 16. PMID: 33373934
  • Ahmad SF, Panigrahi M, Chhotaray S, Pal D, Chauhan A, Sonwane A, Parida S, Bhushan B, Gaur GK, Mishra BP, Singh RK. (2020). Population structure and admixture analysis in Frieswal crossbred cattle of India - a pilot study. Anim Biotechnol., 31(1):86-92. doi: 10.1080/10495398.2018.1538013. Epub 2018 Nov 16. PMID: 30444183.
  • Rawat C, Sahoo NR, Wagh SS, Kumar P, Kumar S, Sonwane A, Qureshi S, Kumar A, Panigrahi M. (2019). Association of ACK1, TFRC polymorphism with diarrhoeagenic E. coli adhesion patterns and their jejunal expression profile in Indian Ghurrah pigs. 3 Biotech. 2019 Nov; 9(11):422. doi: 10.1007/s13205-019-1956-5. Epub 2019 Oct 26. PMID: 31696027; PMCID: PMC6815296.
  • Paul A, Punetha M, Kumar S, Sonwane A, Chouhan VS, Singh G, Maurya VP, Sarkar M. (2019). Regulation of steroidogenic function of luteal cells by thrombospondin and insulin in water buffalo (Bubalus bubalis). Reprod Fertil Dev. 2019 Apr;31(4):751-759. doi: 10.1071/RD18188. PMID: 30509339.
  • Mishra GK, Patra MK, Singh LK, Sheikh PA, Upmanyu V, Chakravarti S, Karikalan M, Sonwane A, Singh SK, Das GK, Kumar H, Krishnaswamy N. (2019). Expression of Kisspeptin and its receptor in the hypothalamus of cyclic and acyclic buffalo (Bubalus bubalis). Theriogenology. 2019 Nov; 139:167-177. doi: 10.1016/j.theriogenology.2019.08.009. Epub 2019 Aug 6. PMID: 31419703.
  • Bhat IA, T B S, Somal A, Pandey S, Bharti MK, Panda BSK, B I, Verma M, J A, Sonwane A, Kumar GS, Amarpal, Chandra V, Sharma GT. (2019). An allogenic therapeutic strategy for canine spinal cord injury using mesenchymal stem cells. J Cell Physiol. 2019 Mar; 234(3):2705-2718. doi: 10.1002/jcp.27086. Epub 2018 Aug 21. PMID: 30132873.
  • Paul A, Bharati J, Punetha M, Kumar S, Mallesh VG, Chouhan VS, Sonwane A, Bag S, Bhure SK, Maurya VP, Singh G, Whitworth KM, Sarkar M. (2019). Transcriptional Regulation of Thrombospondins and Its Functional Validation through CRISPR/Cas9 Mediated Gene Editing in Corpus Luteum of Water Buffalo (Bubalus Bubalis). Cell Physiol Biochem. 2019; 52(3):532-552. doi: 10.33594/000000038. PMID: 30897320.
  • Baranwal A, Sonwane A, Chauhan A, Panigrahi M, Sharma AK. Quantification and comparison of TLR2 activity in monocyte-derived macrophages of zebu and crossbred cattle. (2018). Iran J Vet Res. 2018 Fall; 19(4):283-289. PMID: 30774669; PMCID: PMC6361595.
  • Mishra C, Kumar S, Sonwane AA, Yathish HM, Chaudhary R. Sequence Based Structural Characterization and Genetic Diversity Analysis of Full Length TLR4 CDS in Crossbred and Indigenous Cattle. (2017). Anim Biotechnol. 2017 Jan 2;28(1):61-66. doi: 10.1080/10495398.2016.1202837. Epub 2016 Aug 10. PMID: 27715456.
  • Gupta M, Dangi SS, Chouhan VS, Hyder I, Babitha V, Yadav VP, Khan FA, Sonwane A, Singh G, Das GK, Mitra A, Bag S, Sarkar M. (2014). Expression and localization of ghrelin and its functional receptor in corpus luteum during different stages of estrous cycle and the modulatory role of ghrelin on progesterone production in cultured luteal cells in buffalo. Domest Anim Endocrinol. 48:21-32. doi:10.1016/j.domaniend.2014.01.004.
  • Prakash O, Kumar A, Sonwane A, Rathore R, Singh RV, Chauhan A, Kumar P, Renjith R, Yadav R, Bhaladhare A, Baqir M, Sharma D. (2014). Polymorphism of cytokine and innate immunity genes associated with bovine brucellosis in cattle. Mol Biol Rep. 41(5):2815-25. doi: 10.1007/s11033-014-3136-3
  • Ali I, Chouhan VS, Dangi SS, Gupta M, Tandiya U, Hyder I, Yadav VP, Panda RP, Babitha V, Nagar V, Sonwane A, Khan FA, Das BC, Singh G, Bag S, Sarkar M. (2014). Expression and localization of locally produced growth factors regulating lymphangiogenesis during different stages of the estrous cycle in corpus luteum of buffalo (Bubalus bubalis). Theriogenology. 81(3):428-36. doi: 10.1016/j.theriogenology.2013.10.017

Books

  • Anuj Chauhan, Subodh Kumar, Arvind A. Sonwane and Deepak Sharma. 2014. Protocols in Livestock Genome Analysis. Satish Serial Publishing House, New Delhi, India. 209 pp.
  • Mitra, A., Sonwane, A., Singh Y.P. and Kumar, P. (Eds.). 2014. Recent advances in transgenesis in livestock. Division of Animal Genetics, Indian Veterinary Research Institute, Izatnagar, India. 232 pp.

Patents/TM/copy right etc.

  • Invention disclosure form submitted for patent application:
    Dr. Sonwane Arvind Asaram, Dr. Bina Mishra, Dr. C.L. Patel, Dr. Anuj Chauhan, Dr. Subodh Kumar, Dr. Praveen K. Gupta, Dr. Mohini Saini, Dr. B.P. Mishra, Dr. R.K. Singh. (2021). Modular, facile, cell-independent and safer RNA-guided recombinase (RGR) platforms with higher genome targeting capacity for targeted DNA integration and other genome engineering purposes.

Ongoing Projects

  • Evaluation of RNA-guided recombinase (RGR) platform for cell-independent and safer genome engineering in zebrafish vertebrate model (April 2022 to March 2025) (ICAR-CIFE, Mumbai)

Completed Projects

  • Development of RNA-guided recombinase (RGR) platform for targeted DNA integration. (June 2017 to December 2020) (DBT, Govt. of India, New Delhi)

Developed technologies/products/process/ apps etc.

  • Modular, facile, cell-independent and safer RNA-guided recombinase (RGR) platforms with higher genome targeting capacity for targeted DNA integration and other genome engineering purposes.