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डॉ. जीना के

डॉ. जीना के
वैज्ञानिक
जलीय पर्यावरण एवं स्‍वास्‍थ्‍य प्रबंधन
पीएचडी, एआरएस (मछली स्वास्थ्य)
+91-9702927298 / +91-9082357719
और पढ़ें

Research Interests

  • Molecular antiviral immune response and host-pathogen interactions in fish and shellfish
  • Development of diagnostics for fish and shellfish diseases

Academic Interests

M.F.Sc Courses (Course Co-ordinator)

  • Bacterial and Fungal Diseases of finfish and shellfish (AAH 502)
  • Disease Diagnostic Techniques (AAH 507)
  • Fish and Shellfish Immunology (AAH 506)

Research Papers

  • Pani Prasad,K., Shyam, K. U., Banu Husne, Jeena, K., Rahul Krishnan.2016. Infectious Myonecrosis Virus (IMNV) – An alarming viral pathogen to Penaeid shrimps. Aquaculture: DOI: 10.1016/j.aquaculture.2016.12.021.
  • Arun Sudhagar, S., Pani Prasad, K., Makesh, M., Bhuvaneswari R. G. and Jeena, K., 2015. Characterization and production of polyclonal antisera against pangasius (Pangasianodon hypophthalmus) serum immunoglobulin IgM derived from DEAE cellulose based ion exchange chromatography. Aquaculture Research, 46( 6) :1417–25.
  • Jeena, K., Pani Prasad, K, Pathan M. K., Gireesh Babu, P., Tripathi, G., Sudhagar,A., Srinivas P. Rao. 2013. Expression profile of Penaeus monodon Ubiquitin conjugating enzyme (PmUbc) at protein level in White Spot Syndrome Virus challenged shrimp. Indian Journal of Virology, 24(1): 48-53.
  • Pathan, M.K., Gireesh Babu, P., Pavan-Kumar, A., Jeena, K., Sharma, R., Makesh, M., PaniPrasad, K. and Krishna, G., 2013. In vivotherapeutic efficacy of recombinant Penaeus monodon antiviral protein (rPmAV)administered in three different forms to W S S V i n f e c t e d P e n a e u s m o n o d o n . Aquaculture, 376-379: 64-67.
  • Pani Prasad, K, and Jeena, K. 2013. Advances in aquatic animal health management. International journal of bio-technology and research,31 (2): 35-44.
  • Jeena, K., Pani Prasad, K., Pathan, M.K. and Gireesh Babu, P., 2012. Expression profiling of WSSV ORF 199 and shrimp ubiquitin conjugating enzyme in WSSV infected P. monodon. Asian Australasian Journal of Animal Sciences. 28(8): 1184-1189.

Peer-Reviewed Research And Review Articles

  • Jiji, A., Sanil, N.K., Poojary, N., Kezhedath, J., Krishnan, S., Bedekar, M.K. and Rajendran, K.V., 2025. First Report of Dual Infection of Hepatopancreatic Parvovirus and Enterocytozoon hepatopenaei in Wild and Farmed Macrobrachium rosenbergii. Journal of Fish Diseases, p.e14165.
  • Rajeshwar, B.N., Kumar, T.S., Jithendran, K.P., Bedekar, M.K., Kumar, H.S., Jeena, K., Pathan, M.A. and Rajendran, K.V., 2025. Experimental infection study reveals differential susceptibilities of Penaeus monodon and Penaeus vannamei to Enterocytozoon hepatopenaei. Journal of Invertebrate Pathology, 211, p.108331.
  • Harini, G., Pathak, M.S., Munilkumar, S., Sukhdhane, K.S., Chanu, T.I., Balange, A.K. and Jeena, K., 2025. Unlocking synergies: Enhancing bioremediation, growth, and physiological responses of Penaeus vannamei co-cultured with seaweed. Algal Research, 85, p.103816.
  • Waikhom, D., Kezhedath, J*., Suresh, S.N., Bedekar, M.K., Varghese, T., Kurcheti, P.P. and Valappil, R.K., 2024. Induction of trained immunity using β-glucan and its protective responses in Nile tilapia, Oreochromis niloticus. Developmental & Comparative Immunology, 157, p.105188.
  • Dinakaran, C., Prasad, K.P., Bedekar, M.K., Jeena, K., Acharya, A. and Poojary, N., 2024. In vitro analysis of the expression of inflammasome, antiviral, and immune genes in an Oreochromis niloticus liver cell line following stimulation with bacterial ligands and infection with tilapia lake virus. Archives of Virology, 169(7), p.148.
  • Mushtaq, Z., Kurcheti, P.P., Jeena, K. and Gireesh-Babu, P., 2024. Short peptidoglycan recognition protein 5 modulates immune response to bacteria in Indian major carp, Cirrhinus mrigala. Developmental & Comparative Immunology, 152, p.105104.
  • Valsalam, A., Bedekar, M.K., Kezhedath, J., Sood, N., Poojary, N., Namdeo, M.S., Shrivastava, N. and Rajendran, K.V., 2024. Isolation, in vitro, and in vivo pathogenicity test of Tilapia lake virus (TiLV) and development of a prognostic semi-quantitative lesion scoring system for differentiating clinical/subclinical infection in farmed tilapia (Oreochromis niloticus L.). Microbial Pathogenesis, 186, p.106475.
  • Chovatia, R.M., Acharya, A., Rasal, K.D., Bedekar, M.K., Jeena, K., Rathinam, R.B., Dinakaran, C. and Tripathi, G., 2024. Ontogeny and tissue specific expression profiles of recombination activating genes (RAGs) during development in Nile tilapia, Oreochromis niloticus. Gene Expression Patterns, 52, p.119358.
  • Prasad, K.P., Krishnan, R., Uthaman, S.K., Kezhedath, J. and Kumar, P.V., 2024. Innate Antiviral Response through Mitochondrial Antiviral Signaling Protein (MAVS) in Fish - A Review. Fish Pathology, 59(2), pp.39-53.
  • Rajendran, K.V., Sood, N., Rao, B.M., Valsalam, A., Bedekar, M.K., Jeena, K., Pradhan, P.K., Paria, A., Swaminathan, T.R., Verma, D.K. and Sood, N.K., 2023. Widespread occurrence of Tilapia parvovirus in farmed Nile tilapia Oreochromis niloticus from India. Journal of Fish Diseases.
  • Valsalam, A., Rajendran, K.V., Kezhedath, J., Godavarikar, A., Sood, N. and Bedekar, M.K., 2023. Development of an indirect ELISA test for the detection of Tilapia lake virus (TiLV) in fish tissue and mucus samples. Journal of Virological Methods, 315, p.114707.
  • Mushtaq, Z., Prasad, K.P., Jeena, K., Rajendran, K.V., Martina, P. and Babu, P.G., 2023. Class a scavenger receptor-A5 gene in Cirrhinus mrigala: Cloning, characterisation and expression patterns in response to bacterial infection. Gene, 848, p.146897.
  • Waikhom, D., Kezhedath, J*., Krishnan, R., Varghese, T., Kurcheti, P.P. and Valappil, R.K., 2022. Βeta-glucan stimulation induces trained immunity markers in common carp, Cyprinus carpio. Fish & Shellfish Immunology, 131, pp.855-861.
  • Krishnan, R., Jeena, K. and Kurcheti, P.P., 2021. Nervous necrosis virus induced oxidative imbalance and host associated antioxidant response in Asian seabass brain. Aquaculture, 531, p.735809.
  • Krishnan, R., Kurcheti, P.P., Mushtaq, Z. and Jeena, K., 2019. Interferon-regulatory factors, IRF3 and IRF7 in Asian seabass, Lates calcarifer: Characterization, ontogeny and transcriptional modulation upon challenge with nervous necrosis virus. Fish & Shellfish Immunology, 89, pp.468-476.
  • Krishnan, R., Babu, P.G., Jeena, K., Tripathi, G. and Prasad, K.P., 2018. Molecular characterization, ontogeny and expression profiling of mitochondrial antiviral signaling adapter, MAVS from Asian seabass Lates calcarifer, Bloch (1790). Developmental & Comparative Immunology, 79, pp.175-185.
  • Krishnan, R., Jeena, K., Mushtaq, Z., Shyam, K.U. and Kurcheti, P.P., 2018. Antiviral activity of transiently expressed mitochondrial antiviral signaling adapter, MAVS orthologue from Asian seabass. Fish & Shellfish Immunology, 76, pp.183-186.
  • Krishnan, R., Jeena, K. and Prasad, K.P., 2018. Preliminary investigations on the role of Drp-1 dependent mitochondrial fission in attenuating RLR downstream signaling during nervous necrosis virus infection. Fish & Shellfish Immunology, 80, pp.618-623.
  • Jeena, K., Krishnan, R., Shyam, K.U., Babu, P.G., Lakra, W.S., Purushothaman, C.S. and Prasad, K.P., 2018. Dynamics of Infection in Selected Tissues of White Spot Syndrome Virus-Infected Litopenaeus vannamei. Int. J. Curr. Microbiol. App. Sci, 7(6), pp.3003-3008.
  • Kokkattunivarthil, S., Krishnan, R., Kezhedath, J*. and Prasad, K.P., 2018. New set of PCR primers for SYBR green-based qPCR detection of IMNV in India. Aquaculture, 495, pp.726- 730.
  • Kurcheti Pani Prasad, K.U. Shyam, Husne Banu, K. Jeena, Rahul Krishnan (2017). Infectious myonecrosis virus (IMNV)-An alarming viral pathogen to penaeid shrimps. Aquaculture, 477, pp.99-105.
  • K.U. Shyam, K. Jeena, Pani Prasad K*, Rathore G. and Tripathi G., 2017. Surveillance status for infectious myonecrosis virus in Indian shrimp aquaculture. Indian J. Fish., 64(2), pp.69-75.
  • Dhanapal, S., Rajukumar, K., Kezhedath, J., Semmannan, K., Kumar, M., Shrivastava, D., Bano, F.H., Kulkarni, D. and Singh, V.P., 2017. Pulmonary Alveolar Macrophages Reveal Higher Basal Cytokine mRNA Expression than Peripheral Blood Leucocytes in Healthy Piglets. Journal of Animal Research, 7(4), pp.629-634.
  • Jayaramu, P.K., Tripathi, G., Kumar, A.P., Kezhedath, J., Pathan, M.K. and Kurcheti, P.P., 2017. Studies on expression pattern of toll-like receptor 5 (TLR5) in Edwardsiella tarda infected Pangasianodon hypophthalmus. Fish & Shellfish Immunology, 63, pp.68-73.
  • Arun Sudhagar, S., Prasad, K.P., Makesh, M., RathiBhuvaneswari, G. and Jeena, K., 2015. Characterization and production of polyclonal antisera against pangasius (Pangasianodon hypophthalmus) serum immunoglobulin IgM derived from DEAE cellulose based ion exchange chromatography. Aquaculture Research, 46(6), pp.1417-1425.
  • Pathan, M., Gireesh-Babu, P., Pavan-Kumar, A., Jeena, K., Sharma, R., Makesh, M., Prasad, K.P. and Krishna, G., 2013. In vivo therapeutic efficacy of recombinant Penaeus monodon antiviral protein (rPmAV) administered in three different forms to WSSV infected Penaeus monodon. Aquaculture, 376, pp.64-67.
  • Keezhedath, J., Kurcheti, P.P., Pathan, M.K., Babu, G.P., Tripathi, G., Sudhagar, A. and Rao, S.P., 2013. Expression profile of Penaeus monodon ubiquitin conjugating enzyme (PmUbc) at protein level in white spot syndrome virus challenged shrimp. Indian Journal of Virology, 24(1), pp.48-53.
  • Jeena, K., Prasad, K.P., Pathan, M.K. and Babu, P.G., 2012. Expression profiling of WSSV ORF 199 and shrimp ubiquitin conjugating enzyme in WSSV Infected Penaeus monodon. Asian-Australasian Journal of Animal Sciences, 25(8), p.1184.

Book Chapter

  • Kumar, S.H., Stephen, J., Jeena, K., Lekshmi, M., Sreedharan, K. and Valappil, R.K., 2023. Shrimp Health and Microbiome. In Microbiome of Finfish and Shellfish (pp. 181- 201). Singapore: Springer Nature Singapore.

Sr. No. Title of project Funding agency From To Budget lakhs Role Status
1 Application of heterologous prime and boost strategies for immunoprophylaxis in Tilapia, Oreochromis niloticus ICAR-CIFE 2022 2025 38.0 PI Completed
2 Referral Laboratory under the National Surveillance Programme for Aquatic Animal Diseases PMMSY - Dept. of Fisheries GoI 2022 2026 29.10 Co-PI Ongoing
3 Development of CRISPR based diagnostic test for detection of fish and shellfish viruses ICAR-CRP on Vaccines & Diagnostics 2022 2025 173.05 Co-PI Ongoing
4 Characterization and utilization of sulfated polysaccharides extracted from red seaweed, Gracilaria spp. co-cultured with Penaeus vannamei CSIR-INSPIRE 2024 2027 28.0 Co-PI Ongoing
5 National Surveillance Programme for Aquatic Animal Diseases (NSPAAD) Phase 2 PMMSY-Dept. of Fisheries GoI 2022 2025 53.72 Co-PI Completed
6 Establishment of a Bio-resource Facility of Zebrafish (Danio rerio): A National Genetic Repository for Wild Type and Inbred Zebrafish- Phase I PMMSY-NFDB GoI 2023 2025 70.0 Co-PI Ongoing
7 All India Network Project on Assessment of AMR in Fisheries and Livestock ICAR Network Project 2018 2025 40.0 Co-PI Ongoing
8 Characterization of Mucosal Immunoglobulins in Tilapia and Development of ELISA for Diagnosis of Tilapia Lake Virus (TiLV) Infection DBT,Govt. of India 2019 2022 35.09
360
Co-PI Completed
9 Development of monoclonal antibody against Flavobacterium columnare & its use in Rapid Disease Diagnosis ICAR-CIFE 2019 2021 28.0 Co-PI Completed
10 Propagation and Utilization of Red Seaweed, Gracilaria Spp. for Sustainable Shrimp Aquaculture ICAR-CIFE 2023 2025 25.0 Co-PI Completed
11 Valorization of Fruit and Vegetable Waste for Aquafeed ICAR-CIFE 2022 2025 25.0 Co-PI Completed
12 Enhancing the Utilisation of Non-food Fish and Seaweed through Technology Refinement and Upscaling ICAR-CIFE 2018 2020 10.0 Co-PI Completed
13 Studies on Host Pathogen Interactions and Development of Nano-based Diagnostics for Betanodavirus Infection in Lates calcarifer ICAR-CIFE 2015 2018 35.0 Co-PI Completed